21-Deoxycortisol-d8
Product Specifications
CAS Number
2479914-04-8
Target
Endogenous Metabolite
Related Pathways
Metabolism
Bioactivity
21-Deoxycortisol-d8 is a deuterated compound of 21-Deoxycortisol. 21-Deoxycortisol has a CAS number of 641-77-0. 21-Deoxycortisol is a corticosteroid metabolite of 17-hydroxyprogesterone produced in the adrenal glandvia11-hydroxylation by 11β-hydroxylase.1,2Serum levels of 21-deoxycortisol are elevated in patients with congenital adrenal hyperplasia that are heterozygous for mutations inCYP2A21, the gene encoding steroid 21-hydroxylase, and have been used as a biomarker for the detection of 21-hydroxylase deficiencies.
Smiles
C[C@@]12[C@]([C@]3([C@@]([C@]4(C)C(C(C3)([2H])[2H])=C(C(=O)C(C4)([2H])[2H])[2H])([C@@H](O)C1)[H])[H])(CC[C@@]2(C(C([2H])([2H])[2H])=O)O)[H]
Molecular Formula
C21H22D8O4
Molecular Weight
354.51
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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