UNC-4219 (TFA)
UNC-4219 TFA is a negative control for the CBX7-H3 antagonist UNC3866 (HY-100832) and does not interact with CBX7 at high concentrations[1].
Product Specifications
CAS Number
[1872382-50-7]
UNSPSC
12352005
Target
Histone Methyltransferase
Type
Reference compound
Related Pathways
Epigenetics
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/unc-4219-tfa.html
Smiles
OC(C(F)(F)F)=O.O=C(C1=CC=C(C=C1)C(C)(C)C)N[C@H](C(N(C)[C@@H](C)C(N[C@@H](CC(C)C)C(N[C@@H](CCCCN(CC)CC)C(N[C@@H](CO)C(OC)=O)=O)=O)=O)=O)CC2=CC=CC=C2
Molecular Formula
C46H69F3N6O10
Molecular Weight
923.07
References & Citations
[1]Stuckey JI, et al. A cellular chemical probe targeting the chromodomains of Polycomb repressive complex 1. Nat Chem Biol. 2016 Mar;12 (3) :180-7. doi: 10.1038/nchembio.2007. Epub 2016 Jan 25. Erratum in: Nat Chem Biol. 2019 Aug;15 (8) :846.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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