Cantleyoside

Product Specifications

CAS Number

32455-46-2

Target

Sirtuin, NF-κB, AMPK

Related Pathways

NF-κB, Chromatin/Epigenetic, DNA Damage/DNA Repair, PI3K/Akt/mTOR signaling

Purity

0.9985

Bioactivity

Cantleyoside, a natural cyclic enol ether terpene glycoside from Pterocephalus hookeri, has anti-inflammatory and pro-apoptotic effects, inhibiting inflammatory responses and promoting apoptosis in HFLS-RA cells through activation of the AMPK/Sirt1/NF-κB signaling pathway.

Smiles

O([C@H]1[C@]2([C@@](C(C(OC)=O)=CO1)(C[C@H](OC(=O)C=3[C@@H](CC=O)[C@@H](C=C)[C@H](O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)OC3)[C@@H]2C)[H])[H])[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O