Lipid TD5
Product Specifications
Target
Others
Related Pathways
Others
Bioactivity
Lipid TD5, an ionizable cationic lipid (pKa = 7.3), is utilized in the creation of lipid nanoparticles (LNPs) for mRNA delivery both in vitro and in vivo. These LNPs are internalized via endocytosis in a serotonin (5-HT) receptor subtype 1A-dependent manner in primary mouse astrocytes. When administered intrathecally, LNPs containing lipid TD5 preferentially target the brain over the liver and spleen in mice.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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