Lipid I97
Product Specifications
CAS Number
3046404-81-0
Target
Others, Liposome
Related Pathways
Metabolism, Others
Bioactivity
Lipid I97 is an ionizable cationic lipid derived from vitamin B5 with a pKa of 6.23. It has been utilized in the formation of lipid nanoparticles (LNPs) for mRNA delivery in vivo. In mice, LNPs with lipid I97 encapsulating luciferase mRNA specifically accumulate in the spleen and lymph nodes. Additionally, LNPs containing lipid I97 with mRNA encoding hemagglutinin A trigger the production of IgG1 and IgG2 in mice.
Smiles
[C@H](C(COC(CCCC(OCC(CCCCCCCC)CCCCCC)=O)=O)(C)C)(OC(CCCC(OCC(CCCCCCCC)CCCCCC)=O)=O)C(NCCC(OCCN(C)C)=O)=O
Molecular Formula
C55H102N2O11
Molecular Weight
967.41
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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