CDX-3379
Product Specifications
Target
EGFR
Related Pathways
Tyrosine Kinase/Adaptors|||Angiogenesis|||JAK/STAT signaling
Bioactivity
CDX-3379 is a humanized monoclonal antibody inhibitor that targets ErbB3. By binding to ErbB3, CDX-3379 prevents its dimerization with other receptors, thus inhibiting ErbB3 phosphorylation. This compound can also inhibit the growth and proliferation of tumor cells. CDX-3379 shows potential for research in tumors expressing ErbB3 and NRG1, such as those found in HNSCC.
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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