Camidanlumab tesirine
Product Specifications
CAS Number
1853239-04-9
Target
Antibody-Drug Conjugates (ADCs) |||Interleukin
Related Pathways
Immunology/Inflammation|||Antibody-drug Conjugate/ADC Related
Bioactivity
Camidanlumab tesirine (ADCT 301) is an ADC consisting of a human IgG1 antibody, HuMax-TAC, targeting CD25, which is conjugated through a dipeptide-cleavable linker to pyrrolobenzodiazepine (PBD) dimer payloads. The drug-antibody ratio (DAR) of Camidanlumab tesirine is 2.3. It binds to human CD25 with picomolar affinity and exhibits potent and selective cytotoxicity against human lymphoma cell lines expressing CD25.
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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