NC762
Product Specifications
Target
Others, TNF
Related Pathways
Others, Apoptosis
Bioactivity
NC762 is a humanized IgG1κ monoclonal antibody that targets human B7-H4 (B7 homolog 4) . Its Fc region contains three point mutations (S239D/A330L/I332E; DLE) to enhance binding to CD16a (FcγRIIIa), leading to increased antibody-dependent cellular cytotoxicity (ADCC) . By binding to tumor-expressed B7-H4, NC762 inhibits tumor growth in vivo. This compound can be utilized in research on advanced or metastatic solid tumors.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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