M6903
Product Specifications
Target
Immunology/Inflammation related
Related Pathways
Immunology/Inflammation
Bioactivity
M6903 is a humanized IgG2 monoclonal antibody that targets T-cell immunoglobulin and mucin domain 3 (TIM-3), with a binding affinity (KD) of 2.3 nM for human TIM-3. By binding to TIM-3, M6903 blocks the interaction of TIM-3 with phosphatidylserine (PtdSer), carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1), and galectin-9 (Gal-9) . This blockade helps alleviate TIM-3-mediated T-cell inhibition, promoting antigen-specific T-cell activation and enhancing antitumor immunity. M6903 holds promise for cancer research.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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