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Getagozumab

Product Specifications

CAS Number

2642374-04-5

Target

Endothelin Receptor

Related Pathways

GPCR/G Protein

Purity

0.989

Bioactivity

Getagozumab is a humanized IgG4-kappa monoclonal antibody that specifically targets endothelin receptor type A (EDNRA) with potent antagonistic activity. Getagozumab significantly lowered pulmonary arterial pressure in both hypoxia-induced and monocrotaline (MCT) -induced pulmonary arterial hypertension (PAH) monkey models and further attenuated the associated pulmonary arterial and right ventricular hypertrophy.

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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