Getagozumab
Product Specifications
CAS Number
2642374-04-5
Target
Endothelin Receptor
Related Pathways
GPCR/G Protein
Purity
0.989
Bioactivity
Getagozumab is a humanized IgG4-kappa monoclonal antibody that specifically targets endothelin receptor type A (EDNRA) with potent antagonistic activity. Getagozumab significantly lowered pulmonary arterial pressure in both hypoxia-induced and monocrotaline (MCT) -induced pulmonary arterial hypertension (PAH) monkey models and further attenuated the associated pulmonary arterial and right ventricular hypertrophy.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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