REGN5093-M114
Product Specifications
Target
C-Met/HGFR, Antibody-Drug Conjugates (ADCs), Microtubule Associated
Related Pathways
Antibody-drug Conjugate/ADC Related, Cytoskeletal Signaling, Tyrosine Kinase/Adaptors
Bioactivity
REGN5093-M114 is a bispecific antibody-drug conjugate (ADC) that targets two epitopes of the MET receptor tyrosine kinase, effectively inhibiting NSCLC cell proliferation and demonstrating antitumor activity in mouse models. REGN5093-M114 is composed of the human monoclonal anti-MET antibody Davutamig and a tubulin-inhibiting linker-payload.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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