ABP-102
Product Specifications
Target
Integrin, HER
Related Pathways
Angiogenesis, Cytoskeletal Signaling, JAK/STAT signaling, Tyrosine Kinase/Adaptors
Bioactivity
ABP-102 (CT P72) is a tetravalent IgG1-[L]-scFv bispecific t-cell adduct (BiTE) that acts as a CD3 modulator and selective HER2 modulator for the selective targeting of HER2 overexpressing tumors. ABP-102 showed cytotoxicity in HER2-overexpressing models of breast and gastric cancers, while significantly decreasing activity against HER2 low level cells, twice as effective as rununmotamab.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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