Ianalumab (FUT8-KO)
Product Specifications
Target
Apoptosis
Related Pathways
Apoptosis
Bioactivity
Ianalumab (FUT8-KO) is a humanized, deglycosylated antibody targeting BAFF-R. It inhibits the interaction between BAFF and BAFF-R, antagonizing the apoptosis protection mediated by BAFF. Additionally, Ianalumab (FUT8-KO) exhibits antibody-dependent cellular cytotoxicity (ADCC) that relies on the activation of effector cells mediated by immune receptor tyrosine-based activation motifs (ITAM) .
Smiles
O=C1NC(=O)C(N2C3=NC=CC=C3C4=CC(=CC=C42)CN5CCC(CN(C)CCN6CCN(CC7=CC=C(C=C7)C8=CC(=NN=C8N)C=9C=CC=CC9O)CC6)CC5)CC1
Molecular Formula
C47H54N10O3
Molecular Weight
807
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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