Trastuzumab rezetecan

Product Specifications

CAS Number

2924909-11-3

Target

EGFR|||Antibody-Drug Conjugates (ADCs)

Related Pathways

Angiogenesis|||Antibody-drug Conjugate/ADC Related|||JAK/STAT signaling|||Tyrosine Kinase/Adaptors

Bioactivity

Trastuzumab rezetecan (SHR-A1811) is an antibody-drug conjugate (ADC) targeting HER2. It is composed of a humanized anti-HER2 antibody, a cleavable linker MC-Gly-Gly-Phe-Gly, and an effective payload of the topoisomerase I inhibitor Rezetecán. Trastuzumab rezetecan is utilized in the research of HER2-positive breast cancer.