What is the catalog number for HGS101?

The catalog number for HGS101 is T9901A-1812.

What sizes are available for HGS101?

HGS101 is available in the following size(s): 1 mg, 5 mg.

How many pack sizes does HGS101 come in?

HGS101 is available in 2 different pack sizes.

HGS101 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures HGS101?

HGS101 is manufactured by Molfinity.

What is the estimated delivery time for HGS101?

Estimated delivery time for HGS101 is approximately 10 business day(s), depending on your location.

HGS101

Product Specifications

Target

CCR, HIV Protease

Related Pathways

GPCR/G Protein, Immunology/Inflammation, Microbiology/Virology, Proteases/Proteasome

Bioactivity

HGS101 is a fully humanized CCR5 monoclonal antibody that exhibits high affinity for CCR5. It binds to the second extracellular loop (ECL-2) and functions as a signaling antagonist. HGS101 restores the inhibitory effect of Maraviroc in Maraviroc-resistant HIV-1 infected PBMCs. In an uninfected simian immunodeficiency virus model of rhesus monkeys, HGS101 shows anti-HIV activity by inhibiting CCR5 signaling.