CE-355621
Product Specifications
Target
C-Met/HGFR
Related Pathways
Tyrosine Kinase/Adaptors
Bioactivity
CE-355621 is a humanized anti-c-Met IgG1 monoclonal antibody. It effectively binds to human c-Met in A549 cells (KD= 200 pM, IC50= 466 pM) and also binds effectively to c-Met in cynomolgus monkey kidney cells (KD= 610 pM) . CE-355621 inhibits the c-Met signaling pathway by blocking HGF binding and significantly suppresses tumor growth dependent on the c-Met/HGF pathway. It is applicable for research in cancers such as glioblastoma and gastric cancer.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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