ABX-MA1
Product Specifications
CAS Number
561063-60-3
Target
MMP
Related Pathways
Proteases/Proteasome
Bioactivity
ABX-MA1 is a humanized IgG2 monoclonal antibody inhibitor targeting MCAM/MUC18. It significantly reduces homotypic aggregation and heterotypic adhesion with HUVEC, as well as the formation of experimental lung metastasis. In A375SM/WM2664 xenograft mouse models, ABX-MA1 effectively suppresses tumor growth, angiogenesis, and MMP-2 expression, indicating potential for melanoma research.
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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