UB-221
Product Specifications
CAS Number
2755114-30-6
Target
Others
Related Pathways
Others
Bioactivity
UB-221 is a humanized IgG1 monoclonal antibody inhibitor that targets IgE. It significantly reduces IgE synthesis by stabilizing the membrane-bound CD23 on B lymphocytes and inhibits FcԑRI-mediated activation and degranulation of basophils. UB-221 lowers IgE levels in cynomolgus monkeys and human IgE (ε, κ) transgenic (hIGHE knock-in) mice, making it relevant for asthma and chronic spontaneous urticaria (CSU) research.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
T-003-55 10 µCi
Agouti-Related Peptide (AgRP) (71-132), Form C amide (Human) - I-125 Labeled
Sign In for Pricing
View Details