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Sym-021

Product Specifications

Target

PD-1/PD-L1

Related Pathways

Cell Cycle/Checkpoint, Immunology/Inflammation, Apoptosis

Bioactivity

Sym-021 is a human monoclonal antibody (mAb) targeting PDCD1/PD-1/CD279. It blocks the binding of PD-L1 and PD-L2 ligands, which stimulates the secretion of interferon IFN-γ and IL-2 and promotes T cell proliferation. Sym-021 shows antitumor activity in PDX mouse models.

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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