Sym-021
Product Specifications
Target
PD-1/PD-L1
Related Pathways
Cell Cycle/Checkpoint, Immunology/Inflammation, Apoptosis
Bioactivity
Sym-021 is a human monoclonal antibody (mAb) targeting PDCD1/PD-1/CD279. It blocks the binding of PD-L1 and PD-L2 ligands, which stimulates the secretion of interferon IFN-γ and IL-2 and promotes T cell proliferation. Sym-021 shows antitumor activity in PDX mouse models.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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