VTX-0811
Product Specifications
Target
TNF|||NF-?B|||c-Myc
Related Pathways
Apoptosis|||Cell Cycle/Checkpoint|||NF-?B
Bioactivity
VTX-0811 is a human IgG4 monoclonal antibody (mAb) that targets PSGL1/CD162. It modulates immune signaling pathways by enhancing TNF-?/NF-?B and chemokine-mediated signaling while reducing oxidative phosphorylation, fatty acid metabolism, and Myc signaling. VTX-0811 increases the proportion of CD8+ T cells among infiltrating T cells and exhibits antitumor activity in humanized mouse PDX models of melanoma.
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
![Rabbit Polyclonal POLR3B Antibody [PerCP]](https://cdn.genprice.uk/genprice/uk/genprice5.webp)
MBS7163850 Inquire
Rabbit anti-Escherichia coli O6:H1 (strain CFT073/700928/UPEC) BARA Polyclonal Antibody
Ask
View Details MBS9342942-01 48 Well
Bovine Endoplasmic reticulum resident protein 29, ERP29 ELISA Kit
Ask
View Details