Atigotatug (FUT8-KO)
Product Specifications
CAS Number
2733581-82-1
Target
Others
Related Pathways
Others
Bioactivity
Atigotatug (FUT8-KO) is a monoclonal antibody expressed in CHO cells, where the fucosyltransferase 8 gene (FUT8) has been knocked out. The absence of fucose enhances the antibody's ADCC effect. It targets the fucosylated ganglioside GM1 (fuc-GM1) and is an IgG1κ type humanized antibody. Atigotatug can induce immune-mediated tumor cell death, such as in small-cell lung cancer.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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