Lpathomab
Product Specifications
CAS Number
1253114-37-2
Target
LPL Receptor
Related Pathways
GPCR/G Protein
Bioactivity
Lpathomab (LT3015; LT-3000) is a human IgG1 monoclonal antibody (mAb) targeting LPA. It reduces the release of cytokines IL-8 and IL-6 in SKOV3 cells and blocks tumor cell migration triggered by LPA. In Matrigel plug and CNV models, Lpathomab decreases angiogenesis. In the CCI mouse model, it inhibits brain injury. This compound can be utilized for research on brain injury, ovarian cancer, diabetic neuropathy, and spinal cord injury. Recommended isotype control: HumanIgG1kappa, Isotype Control.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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