MG-1131
Product Specifications
Target
NF-κB, Others, IFNAR
Related Pathways
NF-κB, Others, Immunology/Inflammation
Bioactivity
MG-1131 is a human monoclonal antibody (mAb) targeting TIGIT. It activates NF-κB signaling in T cells and enhances NK cell-mediated tumor-killing activity in a PVR-dependent manner. By blocking TIGIT, MG-1131 increases IFN-γ secretion. This compound is applicable for research in antitumor immunity. Recommended isotype control: HumanIgG1kappa, Isotype Control.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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