XOMA-213
Product Specifications
Target
Estrogen Receptor/ERR
Related Pathways
Endocrinology/Hormones
Bioactivity
XOMA-213 (LFA-102; X213) is a human monoclonal antibody (mAb) that specifically targets the PRLR/Prolactin Receptor. It inhibits hPRL-dependent growth of BaF3/hPRLR cells with an EC50 of 0.5 μg/mL. In models such as the Nb2-11-luc xenograft mouse and the DMBA-induced rat breast cancer model, XOMA-213 effectively suppresses PRLR signaling and tumor growth. This compound is applicable in research focused on breast cancer, hyperprolactinemia, and prostate cancer.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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