MP-RM-1
Product Specifications
Target
PI3K|||EGFR|||Akt
Related Pathways
PI3K/Akt/mTOR signaling|||JAK/STAT signaling|||Tyrosine Kinase/Adaptors|||Cytoskeletal Signaling|||Angiogenesis
Bioactivity
MP-RM-1 is a selective murine monoclonal antibody inhibitor that targets the human epidermal growth factor receptor 3 (ErbB-3) . It blocks ErbB-3 activation induced by neuregulin 1 (NRG-1?), facilitates ErbB-3 internalization and degradation, and inhibits downstream signaling pathways like PI3K-Akt. MP-RM-1 shows potential for research on ErbB-3-overexpressing solid tumors such as breast cancer, melanoma, and prostate cancer.
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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