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GSK3178022

Product Specifications

Target

LPL Receptor, Wnt/beta-catenin

Related Pathways

Cytoskeletal Signaling, Stem Cells, GPCR/G Protein

Bioactivity

GSK3178022 is a human IgG1 monoclonal antibody (mAb) that targets LRP6. It inhibits the expression of the WNT target genes SP5 and AXIN2 and demonstrates antitumor activity in colorectal cancer RSPO fusion models. The recommended isotype control is HumanIgG1kappa, Isotype Control.

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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