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BMS-986397

Product Specifications

CAS Number

2564486-44-6

Target

Ligand for E3 Ligase, Casein Kinase, Molecular Glues

Related Pathways

PROTAC, Metabolism, Stem Cells

Bioactivity

BMS-986397 is a casein kinase 1 α molecular gel degrading agent based on cereblon, which can promote rapid apoptosis and cell cycle arrest of TP53 wild-type acute myeloid leukemia cells.

Smiles

O=C1N(CC=2C1=CC=C(C(N[C@@H]([C@@](F)(F)F)C3=C(Cl)C=CC=N3)=O)C2)[C@@H]4C(=O)NC(=O)CC4

Molecular Formula

C21H16ClF3N4O4

Molecular Weight

480.82

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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