BMS-986397
Product Specifications
CAS Number
2564486-44-6
Target
Ligand for E3 Ligase, Casein Kinase, Molecular Glues
Related Pathways
PROTAC, Metabolism, Stem Cells
Bioactivity
BMS-986397 is a casein kinase 1 α molecular gel degrading agent based on cereblon, which can promote rapid apoptosis and cell cycle arrest of TP53 wild-type acute myeloid leukemia cells.
Smiles
O=C1N(CC=2C1=CC=C(C(N[C@@H]([C@@](F)(F)F)C3=C(Cl)C=CC=N3)=O)C2)[C@@H]4C(=O)NC(=O)CC4
Molecular Formula
C21H16ClF3N4O4
Molecular Weight
480.82
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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