PLX-4545
Product Specifications
Target
Ligand for E3 Ligase|||Molecular Glues
Related Pathways
PROTAC
Bioactivity
PLX-4545 has oral biological activity and is a cereblon based IKZF2 (zinc finger transcription factor Helios) molecular gel degrading agent that acts on immune suppressive regulatory T cells, reprogramming them into pro-inflammatory effector T cells and enhancing anti-tumor immune response.
Smiles
O([C@@H]1[C@H](CCCC1)N2CC(C2)C3=CC=CC=C3)C=4C=C5C(=CC4)C(=O)N(C5)[C@@H]6C(=O)NC(=O)CC6
Molecular Formula
C28H31N3O4
Molecular Weight
473.56
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Product Datasheet
https://www.targetmol.com/attachment/DataSheet/225668281040633858/T9901A-102
CAS Number
2892065-45-9
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
DZ33986-PE 200 µL/Vial
Anti-African malaria mosquito CLIPB14 ser4 Antibody, PE Conjugate
Ask
View Details 
MBS1064957 Inquire
Recombinant Yersinia enterocolitica serotype O:8 / biotype 1B Probable ubiquinone biosynthesis protein UbiB (ubiB)
Ask
View Details 
