PF-08046054

Product Specifications

Target

Microtubule Associated|||PD-1/PD-L1|||Antibody-Drug Conjugates (ADCs)

Related Pathways

Cytoskeletal Signaling|||Antibody-drug Conjugate/ADC Related|||Immunology/Inflammation|||Cell Cycle/Checkpoint|||Apoptosis

Bioactivity

PF-08046054 (SGN-PDL1V) is an antibody-drug conjugate (ADC) targeting PD-L1, created by linking an anti-PD-L1 antibody with the vedotin drug linker VcMMAE. This compound delivers MMAE intracellularly, exerting direct cytotoxic effects on PD-L1-expressing tumor cells. PF-08046054 is applicable for research in solid tumors.