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Emirodatamab

Product Specifications

CAS Number

2449199-61-3

Target

FLT

Related Pathways

Angiogenesis, Tyrosine Kinase/Adaptors

Bioactivity

Emirodatamab (AMG-427) is an anti-FLT3/CD3 bispecific T-cell engager with an extended half-life. It can induce high cytotoxicity in primary AML progenitor cells and enhance FLT-3 expression. Combining Emirodatamab with anti-PD-1 antibodies increases T-cell dependent cytotoxicity (TDCC) . This compound is under investigation for use in relapsed or refractory AML.

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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