Emirodatamab
Product Specifications
CAS Number
2449199-61-3
Target
FLT
Related Pathways
Angiogenesis|||Tyrosine Kinase/Adaptors
Bioactivity
Emirodatamab (AMG-427) is an anti-FLT3/CD3 bispecific T-cell engager with an extended half-life. It can induce high cytotoxicity in primary AML progenitor cells and enhance FLT-3 expression. Combining Emirodatamab with anti-PD-1 antibodies increases T-cell dependent cytotoxicity (TDCC) . This compound is under investigation for use in relapsed or refractory AML.
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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