Lintuzumab

Product Specifications

CAS Number

166089-32-3

Target

Immunology/Inflammation related|||Others

Related Pathways

Immunology/Inflammation|||Others

Purity

0.986

Bioactivity

Lintuzumab (HuM-195) is a non-coupled humanized mouse monoclonal antibody directed against the cell-surface myelomonocyte differentiation antigen, CD33, with anti-leukemic activity that reduces the production of TNF?-induced pro-inflammatory cytokines and chemokines by AML cells.Lintuzumab has antitumor activity and induces cell death directly via CDC or ADCC. Lintuzumab has anti-tumor activity and induces cell death directly via CDC or ADCC.