What is the catalog number for VEGFR-2-IN-52?

The catalog number for VEGFR-2-IN-52 is T89976.

What sizes are available for VEGFR-2-IN-52?

VEGFR-2-IN-52 is available in the following size(s): 10 mg, 50 mg.

How many pack sizes does VEGFR-2-IN-52 come in?

VEGFR-2-IN-52 is available in 2 different pack sizes.

Is VEGFR-2-IN-52 in stock?

VEGFR-2-IN-52 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures VEGFR-2-IN-52?

VEGFR-2-IN-52 is manufactured by Molfinity.

What is the estimated delivery time for VEGFR-2-IN-52?

Estimated delivery time for VEGFR-2-IN-52 is approximately 10 business day(s), depending on your location.

VEGFR-2-IN-52

Product Specifications

CAS Number

3046428-94-5

Target

Apoptosis, Reactive Oxygen Species, VEGFR

Related Pathways

NF-κB, Apoptosis, Metabolism, Angiogenesis, Tyrosine Kinase/Adaptors, Immunology/Inflammation

Bioactivity

VEGFR-2-IN-52 (compound 14d) serves as a powerful inhibitor of VEGFR-2, exhibiting an IC 50 of 191.1 nM. It effectively reduces the protein expression levels of p-VEGFR-2, MMP9, p-ERK1/2, and p-MEK1. In addition, VEGFR-2-IN-52 demonstrates cytotoxic properties by inducing apoptosis and arresting the cell cycle at the G0/G1 phase, and it enhances the levels of ROS.