What is the catalog number for Z21115?

The catalog number for Z21115 is T89970.

What sizes are available for Z21115?

Z21115 is available in the following size(s): 10 mg, 50 mg.

How many pack sizes does Z21115 come in?

Z21115 is available in 2 different pack sizes.

Z21115 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Z21115?

Z21115 is manufactured by Molfinity.

What is the estimated delivery time for Z21115?

Estimated delivery time for Z21115 is approximately 10 business day(s), depending on your location.

Z21115

Product Specifications

CAS Number

2958668-54-5

Target

PDE

Related Pathways

Metabolism

Bioactivity

Z21115 is an orally effective phosphodiesterase 4 (PDE4) inhibitor that can inhibit PDE4D7 with an IC50 of 10.5 nM. It suppresses the expression of IL-6, TNF-α, and iNOS induced by Lipopolysaccharide. In a DSS-induced mouse colitis model, Z21115 demonstrates anti-inflammatory activity without significant toxicity at doses up to 1 g/kg.