What is the catalog number for PP5-IN-2?

The catalog number for PP5-IN-2 is T89967.

What sizes are available for PP5-IN-2?

PP5-IN-2 is available in the following size(s): 10 mg, 50 mg.

How many pack sizes does PP5-IN-2 come in?

PP5-IN-2 is available in 2 different pack sizes.

Is PP5-IN-2 in stock?

PP5-IN-2 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures PP5-IN-2?

PP5-IN-2 is manufactured by Molfinity.

What is the estimated delivery time for PP5-IN-2?

Estimated delivery time for PP5-IN-2 is approximately 10 business day(s), depending on your location.

PP5-IN-2

Product Specifications

Target

Phosphatase

Related Pathways

Metabolism

Bioactivity

PP5-IN-2, a selective and orally active inhibitor of protein phosphatase 5 (PP5), exhibits an IC 50 of 0.9 μM. This compound activates p53 and leads to the downregulation of cyclin D1 and MGMT, thereby inducing cell cycle arrest and reversing Temozolomide (TMZ) resistance in the U87 MG cell line. Additionally, PP5-IN-2 has demonstrated effective inhibition of tumor growth in the xenograft mouse model.