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Si306

Product Specifications

CAS Number

1640012-88-9

Target

Src|||FAK|||EGFR

Related Pathways

Angiogenesis|||JAK/STAT signaling|||Tyrosine Kinase/Adaptors|||Cytoskeletal Signaling

Bioactivity

Si306, an Src inhibitor, exhibits antitumor activity by reducing the phosphorylation of focal adhesion kinase (FAK) and the expression of epidermal growth factor receptor (EGFR), thereby inhibiting the invasion of human glioblastoma (GBM) .

Smiles

ClC(C=1C=CC=CC1)CN2N=CC=3C(=NC(=NC32)SCCN4CCOCC4)NC=5C=CC=C(Br)C5

Molecular Formula

C25H26BrClN6OS

Molecular Weight

573.94

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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