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YCH3124

Product Specifications

Target

Apoptosis|||DUB

Related Pathways

DNA Damage/DNA Repair|||Apoptosis|||Cell Cycle/Checkpoint|||Ubiquitination

Bioactivity

YCH3124 (compound Z33) is an inhibitor of USP7, exhibiting anti-tumor activity with an IC50 value of 41.9 nM. This compound demonstrates substantial in vitro anti-proliferative effects on various tumor cells, including LNCaP (IC50= 3.6 nM) and CHP-212 (IC50=9.9 nM) . Moreover, YCH3124 induces apoptosis in CHP-212 cells by disrupting the cell cycle process during the G1 phase.

Molecular Formula

C30H34N4O5

Molecular Weight

530.61

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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