Autophagy inducer 5
Product Specifications
Target
Reactive Oxygen Species, Autophagy, JNK
Related Pathways
NF-κB, Metabolism, Immunology/Inflammation, MAPK, Autophagy
Bioactivity
Autophagyinducer 5 (compound 21o) serves as a potent inhibitor of MCF-7 (IC50: 2 μM), making it a potential candidate for breast cancer therapy. It induces autophagy by activating the ROS/JNK signaling pathway, which increases ROS production and JNK phosphorylation, ultimately exerting cytotoxic effects.
Molecular Formula
C41H52N4O3
Molecular Weight
648.88
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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