CSN5-IN-1
Product Specifications
Target
PD-1/PD-L1, E1/E2/E3 Enzyme, Others
Related Pathways
Immunology/Inflammation, Apoptosis, Ubiquitination, Others, Cell Cycle/Checkpoint
Bioactivity
CSN5-IN-1 (compound Ac-11) serves as an inhibitor of CSN5, exhibiting IC50 values of 12.56 μM in FP assay and 19 μM in fluorescence assay. Additionally, it influences cellular protein expression by downregulating PD-L1 and upregulating NEDD8-Cul1.
Molecular Formula
C17H22N2O2S
Molecular Weight
318.43
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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