NLRP3-IN-44
Product Specifications
CAS Number
3040298-34-5
Target
NOD-like Receptor (NLR)
Related Pathways
Immunology/Inflammation
Bioactivity
NLRP3-IN-44 (compound P33), an orally active (approximately 62%) and potent inhibitor of NLRP3, exhibits a dissociation constant (K D) of 17.5 nM. This compound is crucial in the research of diseases mediated by the NLRP3 inflammasome.
Smiles
N(C1=C2C(=C(N=N1)C=3C(O)=C4C(=CC3)OC=C4)C5CCC2CC5)[C@H]6CN(CCO)CCC6
Molecular Formula
C25H30N4O3
Molecular Weight
434.53
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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