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NLRP3-IN-44

Product Specifications

CAS Number

3040298-34-5

Target

NOD-like Receptor (NLR)

Related Pathways

Immunology/Inflammation

Bioactivity

NLRP3-IN-44 (compound P33), an orally active (approximately 62%) and potent inhibitor of NLRP3, exhibits a dissociation constant (K D) of 17.5 nM. This compound is crucial in the research of diseases mediated by the NLRP3 inflammasome.

Smiles

N(C1=C2C(=C(N=N1)C=3C(O)=C4C(=CC3)OC=C4)C5CCC2CC5)[C@H]6CN(CCO)CCC6

Molecular Formula

C25H30N4O3

Molecular Weight

434.53

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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