LY 379196
Product Specifications
Target
PKC
Related Pathways
Chromatin/Epigenetic, Cytoskeletal Signaling
Bioactivity
LY 379196, a potent PKC-β inhibitor (IC 50: 50 nM for PKC βI and 30 nM for PKC βII), effectively suppresses the proliferation of bovine retinal microvascular endothelial cells (BREC) induced by VEGF, IGF-1, and bFGF. This compound serves as an antiproliferative agent for proliferative retinopathy.
Molecular Formula
C30H34N4O5S
Molecular Weight
562.68
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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