2-PPA
Product Specifications
CAS Number
21203-86-1
Target
Potassium Channel, Others
Related Pathways
Membrane transporter/Ion channel, Others
Bioactivity
2-PPA serves as a selective TMEM175 inhibitor (IC 50 =32 μM), primarily influencing lysosomal activity. Through acute inhibition of TMEM175, 2-PPA enhances lysosomal macromolecular catabolism, which in turn boosts macrophage activity and other digestive processes. This compound holds significance in Parkinson's disease research.
Smiles
N=1C=CC(N)=CC1C=2C=CC=CC2
Molecular Formula
C11H10N2
Molecular Weight
170.21
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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