Sigma-1 receptor antagonist 6
Product Specifications
CAS Number
1335032-28-4
Target
Sigma receptor
Related Pathways
GPCR/G Protein
Bioactivity
Sigma-1 receptor antagonist 6 (Compound 12), a σ1R antagonist, demonstrates significant antiallodynic effects by targeting the Sigma-1 receptor (σ1R) . This compound is effective in animal models for neuropathic pain, particularly for reducing mechanical allodynia caused by paclitaxel.
Smiles
N#CC1=C(N=C(C(C#N)=C1C=2C=CC=CC2)N(C)CC#C)NCCCC3CCN(CC=4C=CC=CC4)CC3
Molecular Formula
C32H34N6
Molecular Weight
502.65
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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