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4-FPBUA

Product Specifications

CAS Number

2089636-93-9

Target

Autophagy, mTOR

Related Pathways

PI3K/Akt/mTOR signaling, Autophagy

Bioactivity

4-FPBUA, a semi-synthetic analog of lichen acid, enhances the functionality of cell-based blood-brain barriers (BBB) and increases the transport of β-amyloid (Aβ) in monolayer cells. Additionally, it acts as an inhibitor of mTOR, enhancing cellular autophagy (Autophagy) which can reverse BBB disruption in vivo, making it relevant for research in Alzheimer's disease.

Smiles

C[C@]12C=3C(OC1=CC(O)=C(C(C)=O)C2=O)=C(C(/C=C/C4=CC=C(C=C4)C5=CC=C(F)C=C5)=O)C(O)=C(C)C3O

Molecular Formula

C31H23FO7

Molecular Weight

526.51

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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