PF-05661014
Product Specifications
CAS Number
2153474-85-0
Target
Sodium Channel
Related Pathways
Membrane transporter/Ion channel
Bioactivity
PF-05661014, a demethylated analogue of PF-06526290, selectively inhibits Nav1.3 and Nav1.7 currents by stabilizing the inactivated state through interaction with the D4 VSD. This compound is utilized in research focused on sodium channel modulation.
Smiles
O=C(NC1=CC=C(C=C1)S(=O)(=O)NC2=NC=CS2)NCC=3C=CC=CC3
Molecular Formula
C17H16N4O3S2
Molecular Weight
388.46
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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