PTOTAC HSD17B13 degrader 1
Product Specifications
CAS Number
3046195-01-8
Target
Dehydrogenase, PROTACs
Related Pathways
Metabolism, PROTAC
Bioactivity
PTOTAC HSD17B13 Degrader 1, a PROTAC designed to target 17β-HSD 13 (HSD17B13), incorporates several key components. These include the PROTAC target protein ligand HSD17B13 Degrader 2, the PROTAC Linker tert-Butyl 5-bromoisoindoline-2-carboxylate, and the E3 ubiquitin ligase ligand E3 Ligase Ligand 31. Notably, the conjugate formed by the E3 ubiquitin ligase ligand and the linker is recognized as E3 Ligase Ligand-linker Conjugate 114.
Smiles
O=C1N(C=2C(N1C)=CC(CCCN3CC=4C(C3)=CC=C(C4)C5=CC=6C(C=C5)=CN(N6)[C@@H]7CC[C@@H](CNC(=O)C8=C(F)C(F)=C(O)C(F)=C8)CC7)=CC2)C9C(=O)NC(=O)CC9.Cl
Molecular Formula
C45H45ClF3N7O5
Molecular Weight
856.33
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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